L1 cell adhesion molecules as regulators of tumor cell invasiveness
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چکیده
منابع مشابه
Animal lectins as cell adhesion molecules.
Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners. Focusing on two classes of lectins (selectins and galectins), it is evident that their functionality for mediation of adhesive contacts is becoming increasingly ...
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34. Pajouh, M. S., Nagle, R. B., Breathnach, R., Finch, J. S., Brawer, M. K. and Bowden, G. T. (1991) J. Cancer Res. Clin. Oncol. 117, 144150 Monteagudo, C.. Merino, M. J., San-Juan, J., Liotta, L. A. and Stetler-Stevenson, W. G. (1990) Am. J. Pathol. 136, 585-592 Levy, A. T., Cioce, V., Sobel, M. E., Garbisa, S., Grigioni, W. F., Liotta, L. A. and Stetler-Stevenson, W. G. (1991) Cancer Res. 51...
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The structurally related cell adhesion molecules L1 and Nr-CAM have overlapping expression patterns in cerebellar granule cells. Here we analyzed their involvement in granule cell development using mutant mice. Nr-CAM-deficient cerebellar granule cells failed to extend neurites in vitro on contactin, a known ligand for Nr-CAM expressed in the cerebellum, confirming that these mice are functiona...
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The CD44 proteins form a ubiquitously expressed family of cell surface adhesion molecules involved in cell-cell and cell-matrix interactions. The multiple protein isoforms are encoded by a single gene by alternative splicing and are further modified by a range of post-translational modifications. CD44 proteins are single chain molecules comprising an N-terminal extracellular domain, a membrane ...
متن کاملEndothelial Cell Adhesion Molecules
Endothelial adhesion molecules play an important role in the tissue recruitment of leukocytes in inflammatory conditions such as rheumatoid arthritis. We have investigated the effect of the antirheumatic drug gold sodium thiomalate on adhesion molecule protein and mRNA expression in cultured human endothelial cells. Gold sodium thiomalate inhibited cytokine (TNF, IL-1, IL-4)-stimulated expressi...
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ژورنال
عنوان ژورنال: Cell Adhesion & Migration
سال: 2009
ISSN: 1933-6918,1933-6926
DOI: 10.4161/cam.3.3.8689